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I had Marine call Jeanne on the first turn, followed by her Red Orb power which boosts everyone else's attacks, Benoit was initially using Iron Hand on the boss and then Wind Hand or attacking, Karine was attacking or using restorative itens all the time and Hirado was doing Barrier (you need this to minimize the attack from the boss which can wipe you out quite easily otherwise), Dust Cloude and White Orb. I used Jeanne only to heal. Still it took me 10min... I kept killing the minions as they sprang back to life and stunning/putting it to sleep/paralyzing the boss, also you might need to use Marine's Red Orb several times and keep attacking it until it goes!
Oh and I was playing in normal mode with levels 33, 32, 32 and 26!

I used first Marine red orb, Beniot iron hand, karine attack & Hirado barrier
Then Marine attacked, beniot Iron hand, Karine attack Hirado white orb
When any minions appear I use Maxine and Karine to take them out and keep Beniot & Hirado using iron hand & white orb respectively. I also used Karine to top up HP & MP when needed.

Didn't use Jeanne as the first time I tried I got slaughtered

I'm playing normal mode and levels are M 39 B 38 K 37 & H 35